The purpose of this study is to compare two methods of postoperative pain management in
patients undergoing total knee replacement.

Management of Postoperative Pain After Total Knee Replacement.

Postoperative Pain

Knee Replacement Arthroplasty

Patients undergoing total knee replacement will be assigned at random to receive one of
two methods of postoperative pain management. Patients assigned to nerve block will
receive regional anesthetic nerve block using an indwelling femoral nerve catheter and a
single shot sciatic nerve block. Patients assigned to periarticular injection will
receive periarticular local injection into the periarticular soft tissues at the time of
knee replacement using a combination of ropivacaine, epinephrine, ketorolac, and morphine
sulphate. Additionally, all patients will be given a standardized combination of oral
analgesic medications preoperatively and postoperatively. All patients will receive a
posterior stabilized total knee replacement through an medial parapatellar approach.

Nerve Block

Periarticular Injection

Prospective Randomized Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Postoperative Pain After Total Knee Replacement.

Pain was measured using a linear analog scale for pain, with a scale from 0 (no pain) to
10 points (worst possible pain).

Associate Professor of Orthopedics

Use of additional narcotic medications (as needed), measured in morphine equivalents.

Post-operative quadriceps function was measured by the number of participants who could
perform a straight-leg raise.

Length of stay data were calculated from the medical record.

Participants were questioned at the 6 weeks follow-up visit regarding any neurological
changes that were not present preoperatively.

Preoperative femoral block with indwelling femoral catheter and a single shot sciatic
block.

Injection combination prior to skin closure.

Management of Postoperative Pain After Total Knee Replacement.

About this trial

Study ID

Status

Type

Phase

Placebo

Accepting

Not accepting

Trial Timing

What is this trial about?

What are the participation requirements?

Locations

Location

Status