Low-Level Laser Therapy in Chronic Autoimmune Thyroiditis
Sponsored by University of Sao Paulo General Hospital
About this trial
Last updated 15 years ago
Study ID
Status
Type
Phase
Placebo
Accepting
Not accepting
Trial Timing
Ended 16 years ago
What is this trial about?
What are the participation requirements?
Inclusion Criteria
- Patients previously diagnosed with hypothyroidism induced by chronic autoimmune thyroiditis (CAT). The presence of hypothyroidism, laboratory measurements and ultrasonography criteria were applied to diagnose CAT.
- Significantly elevated concentrations of thyroid peroxidase (TPOAb) and/or thyroglobulin (TgAb) autoantibodies
- Ultrasonography results consistent with CAT
- Patients undergoing LT4 treatment
- Normal (or almost normal) levels of triiodothyronine (T3), thyroxine (T4), free T4 and thyrotropin (TSH)
Exclusion Criteria
- Use of immunosuppressants, immunostimulants, or other drugs that could interfere with the production, metabolism and transport of thyroid hormones
- CAT with normal thyroid function
- CAT with subclinical hypothyroidism
- Thyroid nodules
- Hypothyroidism stemming from post-partum thyroiditis (up to 18 months after gestation)
- History of Graves' disease
- Thyrotropin receptor antibody (TRAb) detectable
- Prior treatment with radioiodine
- Tracheal stenosis
- Pregnancy
- History of ionizing irradiation and/or neoplasia in the cervical area
- Previous surgical intervention in the thyroid
- Thyroid hypoplasia
- Ectopic thyroid
- Serious illness (cancer, ischemic coronary artery disease, stroke, kidney or liver failure, etc.)